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rapK [2017-08-22 17:37:38]
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rapK [2017-08-22 17:37:38]

response regulator aspartate phosphatase, controls ComA activity
locus
BSU18910
pI
5.06
mw
43.68 kDa
protein length
371 aa Sequence Blast
gene length
1113 bp Sequence Blast
function
control of ComA activity
product
response regulator aspartate phosphatase
essential
no
synonyms
yobG
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.4|Protein phosphatases]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.2|Response regulator aspartate phosphatase]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]

    • Gene

    Coordinates
    2,062,150 → 2,063,265

    The protein

    Catalyzed reaction/ biological activity

  • control of [protein|7832489F11F606BCF637EC23BAAB41AD10237EBB|ComA] activity [Pubmed|16816200]

    • Effectors of protein activity

  • binding of [protein|886C1BAE024A9D1A6C7C4F16E5251D5427B8D41E|PhrK] inhibits RapK activity [Pubmed|16816200]

    • Structure

  • [PDB|4I1A] ([protein|A208B4564A50D7BE2630DE40E8FAAF3C16236EE4|RapI], 30% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|C8BF3815578293542D14811C60F4CA78AACF73EB|rapK]-[gene|886C1BAE024A9D1A6C7C4F16E5251D5427B8D41E|phrK]
    description
    [Pubmed|11466295]

    sigma factors

  • [protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH]: sigma factor, [Pubmed|11466295], in [regulon|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH regulon]

    • regulatory mechanism

  • [protein|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|PhoP]: activation, [Pubmed|25666134], in [regulon|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|PhoP regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • induced under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|25666134]
    • view in new tab

    References

  • 11466295,16816200,20817675,25225273,25666134